What is PPSV23?

Pneumococcal polysaccharide vaccine (PPSV23) protects against 23 types of pneumococcal bacteria. It will not prevent all pneumococcal disease.

PPSV23 is recommended for:

  • All adults 65 years of age and older,
  • Anyone 2 through 64 years of age with certain long-term health problems,
  • Anyone 2 through 64 years of age with a weakened immune system,
  • Adults 19 through 64 years of age who smoke cigarettes or have asthma.

Most people need only one dose of PPSV. A second dose is recommended for certain high-risk groups. People 65 and older should get a dose even if they have gotten one or more doses of the vaccine before they turned 65.

Your healthcare provider can give you more information about these recommendations. Most healthy adults develop protection within 2 to 3 weeks of getting the shot.

Some people should not get this vaccine

  • Anyone who has had a life-threatening allergic reaction to PPSV should not get another dose.
  • Anyone who has a severe allergy to any component of PPSV should not receive it. Tell your provider if you have any severe allergies.
  • Anyone who is moderately or severely ill when the shot is scheduled may be asked to wait until they recover before getting the vaccine. Someone with a mild illness can usually be vaccinated.
  • Children less than 2 years of age should not receive this vaccine.
  • There is no evidence that PPSV is harmful to either a pregnant woman or to her fetus. However, as a precaution, women who need the vaccine should be vaccinated before becoming pregnant, if possible.